Transition metal catalyzed Carbon-nitrogen bond forming reactions

Abstract

Carbon-nitrogen (C–N) bond forming reactions are fundamental transformations in nature and also basic processes for the preparation of molecules and materials relevant to human activities. The development of new and efficient reactions for the formation of C–N bonds are therefore of great interest in academic and industrial settings. Progress in the last 20 years has focused mainly in C_sp²–N bond forming processes; however, there is growing range of transition metal catalyzed reactions for the introduction of nitrogen in alkyl frameworks (C_sp³–N bond formation). This article describes a selection of modern catalytic methods for the formation of C–N bonds.